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Drug Target Prediction and Repositioning Using an Integrated Network-Based Approach

The discovery of novel drug targets is a significant challenge in drug development. Although the human genome comprises approximately 30,000 genes, proteins encoded by fewer than 400 are used as drug targets in the treatment of diseases. Therefore, novel drug targets are extremely valuable as the so...

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Detalhes bibliográficos
Main Authors: Emig, Dorothea, Ivliev, Alexander, Pustovalova, Olga, Lancashire, Lee, Bureeva, Svetlana, Nikolsky, Yuri, Bessarabova, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617101/
https://ncbi.nlm.nih.gov/pubmed/23593264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060618
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