Type 1 diabetes mellitus abrogates compensatory augmentation of myocardial neuregulin-1β/ErbB in response to myocardial infarction resulting in worsening heart failure

BACKGROUND: Diabetes mellitus (DM) patients surviving myocardial infarction (MI) exhibit a substantially higher incidence of subsequent heart failure (HF). Neuregulin (NRG)-1 and erythroblastic leukemia viral oncogene homolog (ErbB) receptors have been shown to play a critical role in maintenance of...

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Autors principals: Odiete, Oghenerukevwe, Konik, Ewa A, Sawyer, Douglas B, Hill, Michael F
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617023/
https://ncbi.nlm.nih.gov/pubmed/23530877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-12-52
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