Androgen up-regulates vascular endothelial growth factor expression in prostate cancer cells via an Sp1 binding site

BACKGROUND: Vascular Endothelial Growth Factor (VEGF) is regulated by a number of different factors, but the mechanism(s) behind androgen-mediated regulation of VEGF in prostate cancer are poorly understood. RESULTS: Three novel androgen receptor (AR) binding sites were discovered in the VEGF promot...

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Bibliographic Details
Main Authors: Eisermann, Kurtis, Broderick, Carly J, Bazarov, Anton, Moazam, Mustafa M, Fraizer, Gail C
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616929/
https://ncbi.nlm.nih.gov/pubmed/23369005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-7
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