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Pseudo semiparametric maximum likelihood estimation exploiting gene environment independence for population-based case–control studies with complex samples

Advances in human genetics have led to epidemiological investigations not only of the effects of genes alone but also of gene–environment (G–E) interaction. A widely accepted design strategy in the study of how G–E relate to disease risks is the population-based case–control study (PBCCS). For simpl...

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Detalhes bibliográficos
Main Authors: Li, Yan, Graubard, Barry I.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616753/
https://ncbi.nlm.nih.gov/pubmed/22522235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxs008
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