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Modeling RNA degradation for RNA-Seq with applications

RNA-Seq is widely used in biological and biomedical studies. Methods for the estimation of the transcript's abundance using RNA-Seq data have been intensively studied, many of which are based on the assumption that the short-reads of RNA-Seq are uniformly distributed along the transcripts. Howe...

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Detalles Bibliográficos
Main Authors: Wan, Lin, Yan, Xiting, Chen, Ting, Sun, Fengzhu
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616752/
https://ncbi.nlm.nih.gov/pubmed/22353193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxs001
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