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Chemoenzymatic synthesis of mono- and di-fluorinated Thomsen-Friedenreich (T) antigens and their sialylated derivatives

Fluorinated Thomsen-Friedenreich (T) antigens were synthesized efficient from chemically produced fluorinated monosaccharides using a highly efficient one-pot two-enzyme chemoenzymatic approach containing a galactokinase and a D-galactosyl-β1–3-N-acetyl-D-hexosamine phosphorylase. These fluorinated...

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Autori principali: Yan, Jun, Chen, Xi, Wang, Fengshan, Cao, Hongzhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616747/
https://ncbi.nlm.nih.gov/pubmed/23241945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ob26989a
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