Transcribed pseudogene ψPPM1K generates endogenous siRNA to suppress oncogenic cell growth in hepatocellular carcinoma

Pseudogenes, especially those that are transcribed, may not be mere genomic fossils, but their biological significance remains unclear. Postulating that in the human genome, as in animal models, pseudogenes may function as gene regulators through generation of endo-siRNAs (esiRNAs), antisense RNAs o...

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Autores principales: Chan, Wen-Ling, Yuo, Chung-Yee, Yang, Wen-Kuang, Hung, Shih-Ya, Chang, Ya-Sian, Chiu, Chien-Chih, Yeh, Kun-Tu, Huang, Hsien-Da, Chang, Jan-Gowth
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616710/
https://ncbi.nlm.nih.gov/pubmed/23376929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt047
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