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Chemoprevention of lung tumorigenesis by intranasally administered diindolylmethane in A/J mice

The main reasons for the failure of most chemopreventive agents during clinical trials are poor in vivo bioavailability and dose-limiting side effects. One potential approach to surmount these problems in lung cancer chemoprevention trials could be direct delivery of agents into the pulmonary tissue...

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Hlavní autoři: Qian, Xuemin, Song, Jung Min, Melkamu, Tamene, Upadhyaya, Pramod, Kassie, Fekadu
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616664/
https://ncbi.nlm.nih.gov/pubmed/23239747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs390
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