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siRNA Targeting Hes5 Augments Hair Cell Regeneration in Aminoglycoside-damaged Mouse Utricle

Notch signaling is active during the development of mosaic epithelial sheets and during their turnover and regeneration. After the loss of hair cells in the mosaic sheet of the vestibular sensory epithelium, new hair cells can be spontaneously generated by transdifferentiation of supporting cells. T...

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Detalhes bibliográficos
Main Authors: Jung, Jae Yun, Avenarius, Matt R., Adamsky, Swetlana, Alpert, Evgenia, Feinstein, Elena, Raphael, Yehoash
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616538/
https://ncbi.nlm.nih.gov/pubmed/23439501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.18
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