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Niche-less maintenance of HSCs by 2i

Maintenance of hematopoietic stem cells (HSCs) in vitro has been believed to be difficult due to a lack of complete understanding of HSC quiescence maintained by the niche. Recent evidence suggests that in vitro maintenance of human and mouse long-term HSCs (LT-HSCs) is possible through dual inhibit...

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Detalhes bibliográficos
Main Authors: Masuda, Shigeo, Li, Mo, Izpisua Belmonte, Juan Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616430/
https://ncbi.nlm.nih.gov/pubmed/23357848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.14
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