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Development and Modeling of Arsenic Trioxide Loaded Thermosensitive Liposomes for Anticancer Drug Delivery

A novel delivery system for the anticancer drug arsenic trioxide (ATO) is characterized. The release of ATO from DPPC liposomes with MPPC lysolipid incorporated into the bilayer is measured. There is negligible leakage of ATO from all systems at 25°C. Upon heating the liposomes to 37°C, there is 15%...

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Detalhes bibliográficos
Main Authors: Winter, Nicolas D., Murphy, Ryan K.J., Schatz, George C., O’Halloran, Thomas V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616413/
https://ncbi.nlm.nih.gov/pubmed/20486887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08982104.2010.483597
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