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Diabetes Causes Bone Marrow Endothelial Barrier Dysfunction by Activation of the RhoA–Rho-Associated Kinase Signaling Pathway

OBJECTIVE: Diabetes mellitus causes bone marrow (BM) microangiopathy. This study aimed to investigate the mechanisms responsible for BM endothelial dysfunction in diabetes mellitus. METHODS AND RESULTS: The analysis of differentially expressed transcripts in BM endothelial cells (BMECs) from type-1...

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Main Authors: Mangialardi, Giuseppe, Katare, Rajesh, Oikawa, Atsuhiko, Meloni, Marco, Reni, Carlotta, Emanueli, Costanza, Madeddu, Paolo
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616369/
https://ncbi.nlm.nih.gov/pubmed/23307872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300424
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