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The Wnt/β-catenin/TCF-4 pathway upregulates HMGA1 expression in colon cancer
High Mobility Group A1 (HMGA1) encodes proteins that act as mediators in viral integration, modification of chromatin structure, neoplastic transformation, and metastatic progression. Because HMGA1 is overexpressed in most cancers and has transcriptional relationships with several Wnt-responsive gen...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616152/ https://ncbi.nlm.nih.gov/pubmed/22961697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbf.2876 |
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