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The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability
Cancer cells display numerous abnormal characteristics which are initiated and maintained by elevated mutation rates and genome instability. Chromosomal DNA is continuously surveyed for the presence of damage or blocked replication forks by the DNA Damage Response (DDR) network. The DDR is complex a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616148/ https://ncbi.nlm.nih.gov/pubmed/23195997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2012.11.002 |
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