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Analyzing the cancer methylome through targeted bisulfite sequencing

Bisulfite conversion of genomic DNA combined with next-generation sequencing (NGS) has become a very effective approach for mapping the whole-genome and sub-genome wide DNA methylation landscapes. However, whole methylome shotgun bisulfite sequencing is still expensive and not suitable for analyzing...

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Autors principals: Lee, Eun-Joon, Luo, Junfeng, Wilson, James M., Shi, Huidong
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616138/
https://ncbi.nlm.nih.gov/pubmed/23200671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.10.040
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