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A conserved role for intragenic DNA methylation in alternative pre-mRNA splicing

DNA methylome analysis in a variety of species has revealed elevated 5-methylcytosine at exons relative to introns. These associations raised the possibility that intragenic DNA methylation aids the spliceosome in the process of exon definition. Here, I highlight recent genome-wide associations and...

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Detalhes bibliográficos
Autor principal: Oberdoerffer, Shalini
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616078/
https://ncbi.nlm.nih.gov/pubmed/22771943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.19816
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