Kras Gene Mutation and RASSF1A, FHIT and MGMT Gene Promoter Hypermethylation: Indicators of Tumor Staging and Metastasis in Adenocarcinomatous Sporadic Colorectal Cancer in Indian Population

OBJECTIVE: Colorectal cancer (CRC) development involves underlying modifications at genetic/epigenetic level. This study evaluated the role of Kras gene mutation and RASSF1A, FHIT and MGMT gene promoter hypermethylation together/independently in sporadic CRC in Indian population and correlation with...

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Auteurs principaux: Sinha, Rupal, Hussain, Showket, Mehrotra, Ravi, Kumar, R. Suresh, Kumar, Kapil, Pande, Pankaj, Doval, Dinesh Chandra, Basir, Seemi Farhat, Bharadwaj, Mausumi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616004/
https://ncbi.nlm.nih.gov/pubmed/23573237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060142
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