Clinical Implications of Promoter Hypermethylation in RASSF1A and MGMT in Retinoblastoma

We investigated the epigenetic silencing and genetic changes of the RAS-associated domain family 1A (RASSF1A) gene and the O(6)-methylguanine-DNA methyltransferase (MGMT) gene in retinoblastoma. We extracted DNA from microdissected tumor and normal retina tissues of the same patient in 68 retinoblas...

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Detalhes bibliográficos
Main Authors: Choy, Kwong Wai, Lee, Tom C, Cheung, Kin Fai, Fan, Dorothy S P, Lo, Kwok Wai, Beaverson, Katherine L, Abramson, David H, Lam, Dennis S C, Yu, Christopher B O, Pang, Chi Pui
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2005
Assuntos:
Brief Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501141/
https://ncbi.nlm.nih.gov/pubmed/15799820
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