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An Empirical Evaluation of Normalization Methods for MicroRNA Arrays in a Liposarcoma Study

BACKGROUND: Methods for array normalization, such as median and quantile normalization, were developed for mRNA expression arrays. These methods assume few or symmetric differential expression of genes on the array. However, these assumptions are not necessarily appropriate for microRNA expression a...

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Detalhes bibliográficos
Main Authors: Qin, Li-Xuan, Tuschl, Tom, Singer, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615992/
https://ncbi.nlm.nih.gov/pubmed/23589668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CIN.S11384
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