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Protective effects of prepubertal genistein exposure on mammary tumorigenesis are dependent on BRCA1 expression

This study investigated whether prepubertal dietary exposure to genistein reduces mammary tumorigenesis by up-regulating Brca1 expression in mice. Heterozygous Brca1+/− mice and their wildtype (WT) littermates were fed control AIN93G diet or 500 ppm genistein supplemented AIN93G diet from postnatal...

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Hlavní autoři: de Assis, Sonia, Warri, Anni, Benitez, Carlos, Helferich, William, Hilakivi-Clarke, Leena
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615976/
https://ncbi.nlm.nih.gov/pubmed/21680703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0346
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