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Evidence for protein dephosphorylation as a permissive step in GTP-gamma-S-induced exocytosis from permeabilized mast cells.

Mast cells permeabilized by streptolysin O secrete histamine and lysosomal enzymes in response to provision of a dual effector system comprising Ca2+ and a guanine nucleotide (e.g., GTP-gamma-S2) at concentrations in the micromolar range. These are both necessary and together they are sufficient. Th...

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Publicado en:Cell Regul
Autores principales: Churcher, Y, Kramer, K M, Gomperts, B D
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Cell Biology 1990
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361568/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2129107/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.1.7.523
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