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Selumetinib-Enhanced Radioiodine Uptake in Advanced Thyroid Cancer
BACKGROUND: Metastatic thyroid cancers that are refractory to radioiodine (iodine-131) are associated with a poor prognosis. In mouse models of thyroid cancer, selective mitogen-activated protein kinase (MAPK) pathway antagonists increase the expression of the sodium–iodide symporter and uptake of i...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615415/ https://ncbi.nlm.nih.gov/pubmed/23406027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1209288 |
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