Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene.

To test the hypothesis that agents activating receptors negatively coupled to adenylyl cyclase (AC) can stimulate cell proliferation, we have expressed a human alpha 2-adrenergic receptor (alpha 2-C10) in CCL39 cells and studied the effects of alpha 2-agonists on reinitiation of DNA synthesis in qui...

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Pubblicato in:	Cell Regul
Autori principali:	Seuwen, K, Magnaldo, I, Kobilka, B K, Caron, M G, Regan, J W, Lefkowitz, R J, Pouysségur, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Cell Biology 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361538/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1981685/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.1.6.445
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