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Germline excision of transgenes in Aedes aegypti by homing endonucleases

Aedes (Ae.) aegypti is the primary vector for dengue viruses (serotypes1–4) and chikungunya virus. Homing endonucleases (HEs) are ancient selfish elements that catalyze double-stranded DNA breaks (DSB) in a highly specific manner. In this report, we show that the HEs Y2-I-AniI, I-CreI and I-SceI are...

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Hlavní autoři: Aryan, Azadeh, Anderson, Michelle A. E., Myles, Kevin M., Adelman, Zach N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615334/
https://ncbi.nlm.nih.gov/pubmed/23549343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01603
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