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Transforming Growth Factor-β1 and Laminin-111 Cooperate in the Regulation of Expression of Interleukin-6 and Interleukin-8 in Synovial Fibroblasts

In a recent study we showed that binding of synovial fibroblasts (SF) to laminin-111 (LM-111) in the presence of TGF-β1 induced a significant production of IL-16. Here we go on to investigate the regulation of IL-6 and IL-8 in SF by LM-111 and TGF-β1. Changes in steady state mRNA levels encoding the...

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Autores principales: Felka, Tino, Warstat, Katrin, Kluba, Torsten, Mittag, Falk, Hoberg, Maik, Klein, Gerd, Aicher, Wilhelm K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Master Publishing Group 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615287/
https://ncbi.nlm.nih.gov/pubmed/23675204
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