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The Drosophila Over Compensating Males Gene Genetically Inhibits Dosage Compensation in Males

Male Drosophila are monosomic for the X chromosome, but survive due to dosage compensation. They use the Male Specific Lethal (MSL) complex composed of noncoding roX RNA and histone modifying enzymes to hypertranscribe most genes along the X ∼1.6–1.8 fold relative to each female allele. It is not kn...

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Detalhes bibliográficos
Main Authors: Lim, Chiat Koo, Kelley, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615101/
https://ncbi.nlm.nih.gov/pubmed/23565249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060450
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