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Bringing balance by force: live cell extrusion controls epithelial cell numbers

To function as an intact barrier, epithelia must maintain constant cell numbers despite high rates of turnover. If the rate of death exceeds proliferation, epithelial barrier function could become compromised; if it lags behind proliferation, cells could amass into tumors. Although the balance betwe...

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Detalhes bibliográficos
Main Authors: Eisenhoffer, George T., Rosenblatt, Jody
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615095/
https://ncbi.nlm.nih.gov/pubmed/23273931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2012.11.006
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