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Cyclic mechanical reinforcement of integrin–ligand interactions

Cells regulate adhesion in response to internally-generated and externally-applied forces. Integrins connect the extracellular matrix to the cytoskeleton and provide cells with mechanical anchorages and signaling platforms. Here we show that cyclic forces applied to a fibronectin–integrin α(5)β(1) b...

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Detalhes bibliográficos
Main Authors: Kong, Fang, Li, Zhenhai, Parks, William M., Dumbauld, David W., García, Andrés J., Mould, A. Paul, Humphries, Martin J., Zhu, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615084/
https://ncbi.nlm.nih.gov/pubmed/23416109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.01.015
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