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Combined Fluorescent-Chromogenic In Situ Hybridization for Identification and Laser Microdissection of Interphase Chromosomes

Chromosome territories constitute the most conspicuous feature of nuclear architecture, and they exhibit non-random distribution patterns in the interphase nucleus. We observed that in cell nuclei from humans with Down Syndrome two chromosomes 21 frequently localize proximal to one another and dista...

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Autors principals: Paz, Nerea, Zabala, Amaia, Royo, Félix, García-Orad, África, Zugaza, José L., Parada, Luis A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615066/
https://ncbi.nlm.nih.gov/pubmed/23565206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060238
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