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Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor alpha, epidermal growth factor receptor, c-fos, and c-myc genes.

This study documents a biphasic change in the rate of cell cycle progression and proliferation of T-47D human breast cancer cells treated with synthetic progestins, consisting of an initial transient acceleration in transit through G1, followed by cell cycle arrest and growth inhibition. Both compon...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Musgrove, E A, Lee, C S, Sutherland, R L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 1991
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361499/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1922031/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.10.5032
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