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Host Gene Expression Profiling and In Vivo Cytokine Studies to Characterize the Role of Linezolid and Vancomycin in Methicillin-Resistant Staphylococcus aureus (MRSA) Murine Sepsis Model

Linezolid (L), a potent antibiotic for Methicillin Resistant Staphylococcus aureus (MRSA), inhibits bacterial protein synthesis. By contrast, vancomycin (V) is a cell wall active agent. Here, we used a murine sepsis model to test the hypothesis that L treatment is associated with differences in bact...

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Detalhes bibliográficos
Main Authors: Sharma-Kuinkel, Batu K., Zhang, Yurong, Yan, Qin, Ahn, Sun Hee, Fowler, Vance G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614971/
https://ncbi.nlm.nih.gov/pubmed/23565251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060463
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