BMP2 Genetically Engineered MSCs and EPCs Promote Vascularized Bone Regeneration in Rat Critical-Sized Calvarial Bone Defects

Current clinical therapies for critical-sized bone defects (CSBDs) remain far from ideal. Previous studies have demonstrated that engineering bone tissue using mesenchymal stem cells (MSCs) is feasible. However, this approach is not effective for CSBDs due to inadequate vascularization. In our previ...

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Autori principali: He, Xiaoning, Dziak, Rosemary, Yuan, Xue, Mao, Keya, Genco, Robert, Swihart, Mark, Sarkar, Debanjan, Li, Chunyi, Wang, Changdong, Lu, Li, Andreadis, Stelios, Yang, Shuying
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614944/
https://ncbi.nlm.nih.gov/pubmed/23565253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060473
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