Somatic Mutations in Exocrine Pancreatic Tumors: Association with Patient Survival

KRAS mutations are major factors involved in initiation and maintenance of pancreatic tumors. The impact of different mutations on patient survival has not been clearly defined. We screened tumors from 171 pancreatic cancer patients for mutations in KRAS and CDKN2A genes. Mutations in KRAS were dete...

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Detalhes bibliográficos
Main Authors: Rachakonda, P. Sivaramakrishna, Bauer, Andrea S., Xie, Huaping, Campa, Daniele, Rizzato, Cosmeri, Canzian, Federico, Beghelli, Stefania, Greenhalf, William, Costello, Eithne, Schanne, Michaela, Heller, Anette, Scarpa, Aldo, Neoptolemos, John P., Werner, Jens, Büchler, Markus, Hoheisel, Jörg D., Hemminki, Kari, Giese, Nathalia, Kumar, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614935/
https://ncbi.nlm.nih.gov/pubmed/23565280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060870
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