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The leukocyte integrin LFA-1 reconstituted by cDNA transfection in a nonhematopoietic cell line is functionally active and not transiently regulated.

The functional activity of lymphocyte function-associated antigen 1 (LFA-1) on leukocytes can be regulated by T-cell receptor (TCR) stimulation and pharmacologic agents. It was of interest to determine if functionally active LFA-1 could be reconstituted on a nonhematopoietic, LFA-1-negative cell lin...

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Détails bibliographiques
Publié dans:Cell Regul
Auteurs principaux: Larson, R S, Hibbs, M L, Springer, T A
Format: Artigo
Langue:Inglês
Publié: American Society for Cell Biology 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361493/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1712636/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.1.4.359
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