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Genecentric: a package to uncover graph-theoretic structure in high-throughput epistasis data
BACKGROUND: New technology has resulted in high-throughput screens for pairwise genetic interactions in yeast and other model organisms. For each pair in a collection of non-essential genes, an epistasis score is obtained, representing how much sicker (or healthier) the double-knockout organism will...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
BioMed Central
2013
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3614884/ https://ncbi.nlm.nih.gov/pubmed/23331614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-23 |
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