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Genecentric: a package to uncover graph-theoretic structure in high-throughput epistasis data

BACKGROUND: New technology has resulted in high-throughput screens for pairwise genetic interactions in yeast and other model organisms. For each pair in a collection of non-essential genes, an epistasis score is obtained, representing how much sicker (or healthier) the double-knockout organism will...

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Detalhes bibliográficos
Main Authors: Gallant, Andrew, Leiserson, Mark DM, Kachalov, Maxim, Cowen, Lenore J, Hescott, Benjamin J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614884/
https://ncbi.nlm.nih.gov/pubmed/23331614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-23
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