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Identification of Novel Variant of EML4-ALK Fusion Gene in NSCLC: Potential Benefits of the RT-PCR Method

BACKGROUND: The discovery of the transforming fusion gene of the anaplastic lymphoma kinase (ALK) with the echinoderm microtubule-associated protein like 4 (EML4) as an oncogene in 2007 has led to its validation as a clinical target in NSCLC patients in a short period of time. The inhibition of the...

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Détails bibliographiques
Auteurs principaux: Maus, Martin K. H., Stephens, Craig, Zeger, Gary, Grimminger, Peter P., Huang, Eric
Format: Artigo
Langue:Inglês
Publié: Master Publishing Group 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614856/
https://ncbi.nlm.nih.gov/pubmed/23675251
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