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Association between XmnI Polymorphism and HbF Level in Sickle Cell Disease Patients from Chhattisgarh

The γ(G)-158 (C→T) polymorphism plays important function in the disease severity of sickle cell anemia. The XmnI restriction site at -158 position of the γ(G)-gene is associated with increased expression of the γ(G)-globin gene and higher production of HbF. This study aims to determine the frequency...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bhagat, Sanjana, Patra, Pradeep Kumar, Thakur, Amar Singh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Master Publishing Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614849/
https://ncbi.nlm.nih.gov/pubmed/23675255
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