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Liquid Chromatographic Methods for the Determination of Vildagliptin in the Presence of its Synthetic Intermediate and the Simultaneous Determination of Pioglitazone Hydrochloride and Metformin Hydrochloride

Two reversed-phase liquid chromatographic (RP-LC) methods are described for the determination of two binary mixtures of hypoglycemic agents. In the first method, vildagliptin (VDG) was determined in the presence of 3-amino-1-adamantanol (AAD), a synthetic intermediate and impurity of VDG. In the sec...

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Autors principals: El-Bagary, Ramzia I., Elkady, Ehab F., Ayoub, Bassam M.
Format: Artigo
Idioma:Inglês
Publicat: Master Publishing Group 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614836/
https://ncbi.nlm.nih.gov/pubmed/23675237
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