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TP53 codon 72 Gene Polymorphism Paradox in Associated with Various Carcinoma Incidences, Invasiveness and Chemotherapy Responses

TP53 is the most common mutated gene in human cancers. Approximately half of all human malignancies exhibit TP53 mutations. The TP53 codon 72 polymorphism is a single-nucleotide polymorphism (SNP) in exon 4, resulting in the expression of either arginine (CGC) or proline (CCC) residues. In this arti...

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Detalhes bibliográficos
Main Authors: Lin, Hung-Yu, Huang, Chun-Hsiung, Wu, Wen-Jen, Chang, Li-Ching, Lung, For-Wey
Formato: Artigo
Idioma:Inglês
Publicado em: Master Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614723/
https://ncbi.nlm.nih.gov/pubmed/23675098
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