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Medial Expression of TNF-α and TNF Receptors Precedes the Development of Atherosclerotic Lesions in Apolipoprotein E/LDL Receptor Double Knockout Mice

TNF-α is present in atherosclerotic lesions, activates endothelial adhesion molecule expression, stimulates the release of proinflammatory cytokines and matrix metalloproteinases and promotes smooth muscle cell proliferation and migration. Taken together these observations suggest that TNF-α may be...

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Autori principali: Niemann-Jönsson, Audrey, Söderberg, Ingrid, Lindholm, Marie W, Jovinge, Stefan, Nilsson, Jan, Fredrikson, Gunilla Nordin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Master Publishing Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614629/
https://ncbi.nlm.nih.gov/pubmed/23675033
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