Monitoring Repair of DNA Damage in Cell Lines and Human Peripheral Blood Mononuclear Cells

We introduce a method to follow DNA repair that is suitable for both clinical and laboratory samples. An episomal construct with a unique 8-oxoguanine base at a defined position was prepared in vitro using single-stranded phage harboring a 678 bp tract from exons 5–9 of the human P53 gene. Mixing cu...

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Bibliographic Details
Main Authors: Lee, Hyun-Wook, Lee, Hae-Jung, Hong, Chong-mu, Baker, David J., Bhatia, Ravi, O’Connor, Timothy R.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614353/
https://ncbi.nlm.nih.gov/pubmed/17449003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.03.016
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