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An Acetylation Switch Regulates SUMO-Dependent Protein Interaction Networks
The attachment of the SUMO modifier to proteins controls cellular signaling pathways through noncovalent binding to SUMO-interaction motifs (SIMs). Canonical SIMs contain a core of hydrophobic residues that bind to a hydrophobic pocket on SUMO. Negatively charged residues of SIMs frequently contribu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3614008/ https://ncbi.nlm.nih.gov/pubmed/22578841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.04.006 |
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