Hepatic glucose sensing is required to preserve β cell glucose competence

Liver glucose metabolism plays a central role in glucose homeostasis and may also regulate feeding and energy expenditure. Here we assessed the impact of glucose transporter 2 (Glut2) gene inactivation in adult mouse liver (LG2KO mice). Loss of Glut2 suppressed hepatic glucose uptake but not glucose...

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Detalhes bibliográficos
Main Authors: Seyer, Pascal, Vallois, David, Poitry-Yamate, Carole, Schütz, Frédéric, Metref, Salima, Tarussio, David, Maechler, Pierre, Staels, Bart, Lanz, Bernard, Grueter, Rolf, Decaris, Julie, Turner, Scott, da Costa, Anabela, Preitner, Frédéric, Minehira, Kaori, Foretz, Marc, Thorens, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613916/
https://ncbi.nlm.nih.gov/pubmed/23549084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65538
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