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WNT signaling determines tumorigenicity and function of ESC-derived retinal progenitors
Tumor formation constitutes a major obstacle to the clinical application of embryonic stem cell–derived (ESC-derived) cells. In an attempt to find major extracellular signaling and intrinsic factors controlling tumorigenicity and therapeutic functionality of transplanted ESC-derived retinal progenit...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613909/ https://ncbi.nlm.nih.gov/pubmed/23524971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65048 |
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