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WNT signaling determines tumorigenicity and function of ESC-derived retinal progenitors

Tumor formation constitutes a major obstacle to the clinical application of embryonic stem cell–derived (ESC-derived) cells. In an attempt to find major extracellular signaling and intrinsic factors controlling tumorigenicity and therapeutic functionality of transplanted ESC-derived retinal progenit...

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Detalhes bibliográficos
Main Authors: Cui, Lu, Guan, Yuan, Qu, Zepeng, Zhang, Jingfa, Liao, Bing, Ma, Bo, Qian, Jiang, Li, Dangsheng, Li, Weiye, Xu, Guo-Tong, Jin, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613909/
https://ncbi.nlm.nih.gov/pubmed/23524971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65048
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