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Advances in osteoclast biology reveal potential new drug targets and new roles for osteoclasts

Osteoclasts are multinucleated myeloid lineage cells formed in response to M-CSF and RANKL by fusion of bone marrow-derived precursors that circulate in the blood and are attracted to sites of bone resorption in response to factors, such as sphingosine-1 phosphate signaling. Major advances in unders...

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Detalhes bibliográficos
Autor principal: Boyce, Brendan F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613781/
https://ncbi.nlm.nih.gov/pubmed/23436579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1885
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