Overexpression of the mTERT gene by adenoviral vectors promotes the proliferation of neuronal stem cells in vitro and stimulates neurogenesis in the hippocampus of mice

We sought to construct the adenoviral vector carrying the gene encoding mouse telomerase reverse transcriptase (mTERT), as well as detect its expression and effect on the proliferation of neuronal stem cells. mTERT was amplified by RT-PCR and then the eukaryotic expression vector of pDC-EGFP-TERT wa...

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Detalhes bibliográficos
Main Authors: Liu, Mengying, Hu, Yao, Zhu, Lijuan, Chen, Chen, Zhang, Yu, Sun, Weixiang, Zhou, Qigang
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613735/
https://ncbi.nlm.nih.gov/pubmed/23554775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.26.20110078
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