The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3

Membrane microcompartments of the early endosomes serve as a sorting and signaling platform, where receptors are either recycled back to the plasma membrane or forwarded to the lysosome for destruction. In metazoan cells, three complexes, termed BLOC-1 to -3, mediate protein sorting from the early e...

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Bibliographic Details
Main Authors: John Peter, Arun T., Lachmann, Jens, Rana, Meenakshi, Bunge, Madeleine, Cabrera, Margarita, Ungermann, Christian
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2013
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613695/
https://ncbi.nlm.nih.gov/pubmed/23547030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201210038
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