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CDK-dependent phosphorylation and nuclear exclusion coordinately control kinetochore assembly state

Accurate chromosome segregation requires assembly of the multiprotein kinetochore complex. Prior work has identified more than 100 different kinetochore components in human cells. However, little is known about the regulatory processes that specify their assembly upon mitotic entry and disassembly a...

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Bibliographic Details
Main Authors: Gascoigne, Karen E., Cheeseman, Iain M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613690/
https://ncbi.nlm.nih.gov/pubmed/23530067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201301006
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