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Global analysis of SUMO chain function reveals multiple roles in chromatin regulation

Like ubiquitin, the small ubiquitin-related modifier (SUMO) proteins can form oligomeric “chains,” but the biological functions of these superstructures are not well understood. Here, we created mutant yeast strains unable to synthesize SUMO chains (smt3(allR)) and subjected them to high-content mic...

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Detalhes bibliográficos
Main Authors: Srikumar, Tharan, Lewicki, Megan C., Costanzo, Michael, Tkach, Johnny M., van Bakel, Harm, Tsui, Kyle, Johnson, Erica S., Brown, Grant W., Andrews, Brenda J., Boone, Charles, Giaever, Guri, Nislow, Corey, Raught, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613684/
https://ncbi.nlm.nih.gov/pubmed/23547032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201210019
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